Fox Mulder and Dana Scully both worked at the FBI as partners, a bond between them that led to their becoming lovers. But now they're out of the FBI and have gone their separate ways. Scully works as a staff physician at a Catholic hospital. Her focus these days is on a young boy with an incurable brain disease. Administration wants to give up on him. Scully, who feels a special bond with the boy, does not. Meanwhile, Mulder's focus is on clipping newspaper articles about the paranormal and throwing pencils into his ceiling. Scully and Mulder are brought together again when a special case requires Mulder's expertise, and Scully is prevailed upon to find him. The case involves a pedophile priest who claims he is having psychic visions regarding the whereabouts of a missing FBI agent.

Casey Beldon hated her mother for abandoning her as a child. But when inexplicable events begin to happen, Casey begins to understand why she left. Plagued by merciless dreams and a tortured ghost that haunts her waking hours, she must turn to the only person, Rabbi Sendak, who can make it stop. With the help of Sendak, her best friend Romy and boyfriend Mark, Casey uncovers the source of a family curse dating back to Nazi Germany a creature with the ability to inhabit anyone or anything that is getting stronger with each possession. With the curse unleashed, her only chance at survival is to shut a doorway from beyond our world that has been pried open by someone who was never born.

The notorious Gecko Brothers, two of America's most dangerous criminals, are on the run from the Texas police and the FBI after a crime spree through the Southwest. Across the border in Mexico, the mysterious Carlos offers sanctuary to criminals on the lam, but first they must slip past the border patrol. Enter the Fuller family: Jacob, a minister who has lost his faith and his children, the vulnerable teenage Kate and her younger brother Scott, on a road trip in their new R.V. The Gecko Brothers kidnap the Fullers and high-tail it to freedom with the promise to let the family go once they hook up with their criminal connection in Mexico. The rendezvous point is the Titty Twister, the wildest bar this side of the Rio Grande. The night is full of seductive promise as the group settles back to wait for Carlos and his boys to arrive at sunrise. But unbeknownst to the brothers or their hostages, the management and staff of this particular establishment have a taste for blood--in the vampire sense.

During an otherwise routine babysitting gig, a high-school student is harassed by an increasingly threatening prank caller.