Six unsuspecting college co-eds discover their dorm was once the site of a notorious insane asylum infamous for conducting gruesome lobotomy's on its teenage inmates during the 1930's. When the dorm begins to echo scenes from its torture chamber past, the beautiful heroine questions her sanity and if she will make it out alive.

A young doctor in a US hospital administers a powerful and untested cocktail of drugs to a coma victim. But instead of curing him, it triggers a powerful "out-of-body" experience and enables the patient - a depraved and dangerous loner - to inhabit other people's bodies and, through them, take revenge on the bullying medical students who were accidentally responsible for his condition. The doctor, who was herself a part of this group, is also targeted and as her colleagues are singled out and relentlessly picked off, she realises that she can trust no-one - friend or stranger - as this comatose killer moves in and out of bodies at will, getting ever closer as his murderous supernatural powers increase.

During their nightly poker game a group of lowlifes are terrorized in their own convenience store by a masked killer.

After being the only survivor of the crash of Flight 180, Clear Rivers has locked herself away in the perceived safety of a psychiatric hospital, where she lives in constant terror that Death is coming to claim her, as it did all her friends. Clear may be considered crazy, but she's not wrong. Death is moving toward suburban Route 23, heading south. En route to a weekend getaway with her friends, Kimberly Corman watches helplessly as a logging truck careens out of control and loses its deadly payload, setting off a horrifying chain reaction that leaves twisted metal and dead bodies in its wake--including her own. A moment later, Kimberley finds herself still stuck in on-ramp traffic, with a line of commuters she saw die moments before. It was only a vision, but was it a warning? Shocked into action, Kimberly blocks the cars from joining the traffic on Route 23. The commuters begin to honk and complain--until Kimberly's premonition comes true. Death tears up the highway in a massive pile-up, with those left on the on-ramp narrowly escaping with their lives. But Kimberly knows it s not over. Death will not be cheated so easily for this random group of strangers who must join Kimberly in a race against time to do what all but one of the survivors of Flight 180 couldn't--stay alive.