Jigsaw has disappeared; and with his new apprentice Amanda--the puppet-master behind the cruel, intricate games that have terrified a community and baffled police--he has once again eluded capture and vanished. While city detectives scramble to locate him, Dr. Lynn Denlon is unaware that she is about to become the latest pawn on his vicious chessboard. One night, after finishing a shift at her hospital, Lynn is kidnapped and taken to an abandoned warehouse where she meets Jigsaw, bedridden and on the verge of death. She is told that she must keep the madman alive for as long as it takes another one of his victims, Jeff, to complete a game of his own. Racing against the ticking clock of Jigsaw's own heartbeat, Lynn and Jeff struggle to make it through each of their vicious tests, unaware that he has a much bigger plan for both of them.

When band members are stranded on a country road, excitement of their first tour is diminished by the horrors of a science experiment gone awry. Their pig-human hybrid mutant captors have many horrors in store but true revulsion does not descend until daylight when the extent of their work is revealed.

On a small island off North America's coast, the dead rise to menace the living. Yet...the islanders can't bring themselves to exterminate their loved ones, despite the growing danger from those the once held dear. A rebel among them hunts down all the zombies he can find, only to be banished from the island for assassinating his neighbors and friends. On the mainland, bent on revenge, he encounters a small band of survivors in search of an oasis on which to build a new life. Barely surviving an attack from a mass of ravenous flesh-eaters. They commandeer a zombie-infested ferry and sail to the island. There, to their horror, they discover that the locals have chained the dead inside their homes, pretending to live 'normal' lives...with bloody consequences. What ensues is a desperate struggle for survival and the answer to a question never posed in Romero's Dead films: Can the living ever live in peace with the dead?

Seven strangers are trapped inside an infamous 'House of Horrors' during a Hollywood movie studio tour and forced to tell their most terrifying personal stories to get out alive.