When a shipping container washes ashore, its deadly cargo escapes to wreak havoc on a suburban neighborhood. Is this a terrorist attack or something more sinister? As the military enforce a quarantine, a mother must overcome all the odds to save her estranged daughter.

At her new job in a rundown children's hospital, a nurse desperately tries to keep her patients safe from a plague of random, mysterious attacks.

Mandy Lane. Beautiful. Untouched. High school royalty waiting to be crowned. Since the dawn of Junior year, men have tried to possess her. Some have even died in reckless pursuit of this 16-year-old Texas angel. Chloe and Red invite Mandy out to Red's family ranch for the weekend. Mandy sees it as an excellent opportunity to cement her new friendships. The boys see it as an opportunity to finally get with Mandy Lane. Driving across the Texas landscape, the kids begin to gently chip away at the wall that surrounds her. Joints are smoked. A keg is stolen off a beer truck. Pills are crushed to fine powder and inhaled. Mandy observes it all with the gentle interest of a foreign tourist. And they love her for it. At the ranch, all the boys start to make their move--each one hoping to be the first to attain the unattainable Mandy Lane. However, as night falls and the booze, drugs, and hormones take over, things are said and advances made which can never be reversed. Suddenly, sweet Mandy finds herself pit in a brutal struggle for survival against someone whose interest she has rejected. Forget reading, writing and arithmetic; in high school, learning to be yourself and not succumbing to peer pressure is the ultimate test. And this is one exam that Mandy is determined not to fail.

It's the wedding anniversary of rugged Cleveland police detective "Big Bob" Carter and his chatty wife Ethel and to celebrate, Bob's asked his extended family to cruise to California with them, hoping the joys of the open road might help fuse their frayed connections. No one is particularly happy about it. Eldest daughter, Lynn, worries about her new baby's safety and comfort while her husband, mild-mannered tech geek, Doug, worries about close encounters with his father-in-law. Meanwhile teen daughter, Brenda, detests the idea of leaving her friends for a family bonding trip, while young prankster Bobby is anxious to entertain the family's two German Shepherds, Beauty and Beast. Nevertheless, the entire clan piles into a weathered Suburban pulling Bob's beloved '88 Airstream trailer and heads west. Then, Big Bob takes a detour. Suddenly, the Carter family finds themselves in a desolate stretch of desert, with nothing seemingly alive for miles. When they run into a little unexpected vehicle trouble, they realize they are in dire straits, far from help, with a relentlessly sweltering desert sun overhead. But even as they fight to survive the deadly desert, a far greater threat emerges. Now the Carters become aware that they are not quite as alone as they first thought. There is another group of survivors in the hills surrounding the desert: a genetically mutated, insatiably hungry, blood-thirsty clan--the terrifying offspring of miners left behind in the days when atomic tests spread radioactive fallout across the desert--who will stop at nothing to prey on the Carters one by one. Facing the very depths of savagery, the Carter family must pull together if they are to find any hope of returning to civilized life again--alive.