When two American girls on a bike trip in a remote part of Argentina split up and one of them goes missing, the other must find her before her worst fears are realized.

It's the wedding anniversary of rugged Cleveland police detective "Big Bob" Carter and his chatty wife Ethel and to celebrate, Bob's asked his extended family to cruise to California with them, hoping the joys of the open road might help fuse their frayed connections. No one is particularly happy about it. Eldest daughter, Lynn, worries about her new baby's safety and comfort while her husband, mild-mannered tech geek, Doug, worries about close encounters with his father-in-law. Meanwhile teen daughter, Brenda, detests the idea of leaving her friends for a family bonding trip, while young prankster Bobby is anxious to entertain the family's two German Shepherds, Beauty and Beast. Nevertheless, the entire clan piles into a weathered Suburban pulling Bob's beloved '88 Airstream trailer and heads west. Then, Big Bob takes a detour. Suddenly, the Carter family finds themselves in a desolate stretch of desert, with nothing seemingly alive for miles. When they run into a little unexpected vehicle trouble, they realize they are in dire straits, far from help, with a relentlessly sweltering desert sun overhead. But even as they fight to survive the deadly desert, a far greater threat emerges. Now the Carters become aware that they are not quite as alone as they first thought. There is another group of survivors in the hills surrounding the desert: a genetically mutated, insatiably hungry, blood-thirsty clan--the terrifying offspring of miners left behind in the days when atomic tests spread radioactive fallout across the desert--who will stop at nothing to prey on the Carters one by one. Facing the very depths of savagery, the Carter family must pull together if they are to find any hope of returning to civilized life again--alive.

Casey Beldon hated her mother for abandoning her as a child. But when inexplicable events begin to happen, Casey begins to understand why she left. Plagued by merciless dreams and a tortured ghost that haunts her waking hours, she must turn to the only person, Rabbi Sendak, who can make it stop. With the help of Sendak, her best friend Romy and boyfriend Mark, Casey uncovers the source of a family curse dating back to Nazi Germany a creature with the ability to inhabit anyone or anything that is getting stronger with each possession. With the curse unleashed, her only chance at survival is to shut a doorway from beyond our world that has been pried open by someone who was never born.

The tragic loss of their unborn child has devastated Kate and John, taking a toll on both their marriage and Kate’s fragile psyche as she is plagued by nightmares and haunted by demons from her past. Struggling to regain some semblance of normalcy in their lives, the couple decides to adopt another child. At the local orphanage, both John and Kate find themselves strangely drawn to a young girl named Esther. Almost as soon as they welcome Esther into their home, however, an alarming series of events begins to unfold, leading Kate to believe that there’s something wrong with Esther-this seemingly angelic little girl is not what she appears to be. Concerned for the safety of her family, Kate tries to get John and others to see past Esther’s sweet facade. But her warnings go unheeded until it may be too late…for everyone.