As a deadly battle rages over Jigsaw's brutal legacy, a group of Jigsaw survivors gathers to seek the support of self-help guru and fellow survivor Bobby Dagen, a man whose own dark secrets unleash a new wave of terror.

Frankie Paige is in her twenties. She works as a hairdresser. She has a boyfriend. There are a hundred other girls like Frankie Paige within a mile radius of her Boston apartment. But unlike all of them, things happen to Frankie--terrible things she can't understand or explain. And though she has tried everything to make them stop, they're just getting worse. She goes to doctors and psychologists, but even they can not answer the most important question: why her? At the moment of one her episodes, a chance encounter with a local priest is caught on tape and frightening implications of the incident drive the Vatican to send their own local investigator, Andrew Kiernan. Confronted with the powerful force that has taken over Frankie, Kiernan immediately recognizes the true danger she is in, and he must search in his own soul for the strength to save her life--even if it goes against everything he believes.

Jericho Cane, a beaten down ex-cop, wakes up to another day, oblivious to the struggle that he soon must face. His job as a security specialist alongside his partner Chicago has become a tireless routine of seedy surveillance jobs, and since the death of his wife and child, everything in life which once held any meaning to him is now gone. Following a bizarre confrontation with a crazed homeless man warning him of impending doom, Cane rescues a young woman, Christine York from attackers who have invaded her home. He soon finds himself drawn into a heart-stopping game of cat and mouse, as he realizes that she is the key to a supernatural force of terror, born of prophecy long ago foretold. For she is the unwitting object of desire of what deceptively appears to be just a man, but is in fact the ultimate embodiment of evil--Satan. Now, as the world stands on the brink of the new millennium, it is up to Cane to protect Christine--and all mankind--from witnessing the end of days.

Police shoot and kill a convicted strangler after cornering him in a toy store. As the man is dying, he transfers his soul into a doll.