A remake of the 1974 cult classic, It’s Alive is a gore splattered cautionary tale of the terrifying consequences of experimental drug testing. Bijou Phillips stars as Lenore Harker, a normal High School senior who seems to have it all: a boyfriend who loves her, great grades and a new baby on the way. Above all, she is certain of one thing, the baby she and Frank (James Murray) are expecting is going to be special. The fate of the happy new couple takes a sinister turn as the doctors and nurses delivering their baby are all brutally murdered, leaving just Lenore and her baby miraculously safe. As the police frantically try to unravel the mystery, strange and frightening events begin to occur back at the house. Cocooned in blissful motherhood Lenore is unable to connect the mounting gruesome deaths piling up around her with the sweet child in her arms. As the horrifying truth becomes clear and their home becomes a house of horror, Lenore must choose between ending the life of her baby or sacrificing herself to save the family she loves.

Clive and Elsa are a pair of brilliant scientists whose cutting-edge experiments in genetic engineering make them superstars in their field. As devoted to their careers as they are to one another, they start conducting unauthorized experiments with new animal species that show great promise. Drunk with their god-like powers, they introduce human DNA into one of their creations, producing a creature that is greater than the sum of its parts: a rapidly developing animal/human hybrid that may be a step up on the evolutionary ladder. While this female creature inspires maternal feelings in Elsa, she evokes something far-from-paternal in Clive, something that poses a threat to them all. Then, when this seemingly perfect organism makes a final, shocking metamorphosis, it is mankind itself that is threatened.

Stephen Prentices script is about Darren Mullet, a bullied asthmatic, driven to suicide by his tormented life - ignored by his parents, ridiculed by his teachers and bullied at school. He returns from the dead to pay his teenage tormentors a final visit.

Follows a small group of humans trying to survive in a dystopia populated by the walking dead.